P15.15: Antenal sonographic diagnosis in fetus of periventricular leukomalacia

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Neonatal periventricular leukomalacia: real-time sonographic diagnosis with CT correlation.

The utility of real-time sonography in the diagnosis of neonatal periventricular leukomalacia (PVL) has been described only recently. Six cases are reported of PVL diagnosed by serial real-time scanning. The sonographic findings were correlated with the computed tomographic findings and the clinical history. In five of six infants in whom scanning was performed, characteristic multiseptated per...

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Prenatal Diagnosis of Cystic Periventricular Leukomalacia in a Full Term Fetus

Periventricular leukomalacia is a disorder of white matter injury that is frequently found in premature infants and is the major cause of cerebral palsy. However, only a few cases of periventricular leukomalacia have been reported prenatally. Ultrasound investigation of the periventricular region could provide clues for the prenatal diagnosis and prediction of cerebral palsy. Herein, we report ...

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Animal Models of Periventricular Leukomalacia

Periventricular leukomalacia, specifically characterized as white matter injury, in neonates is strongly associated with the damage of pre-myelinating oligodendrocytes. Clinical data suggest that hypoxia-ischemia during delivery and intrauterine or neonatal infection-inflammation are important factors in the etiology of periventricular leukomalacia including cerebral palsy, a serious case exhib...

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Mouse Models of Periventricular Leukomalacia

We describe a protocol for establishing mouse models of periventricular leukomalacia (PVL). PVL is the predominant form of brain injury in premature infants and the most common antecedent of cerebral palsy. PVL is characterized by periventricular white matter damage with prominent oligodendroglial injury. Hypoxia/ischemia with or without systemic infection/inflammation are the primary causes of...

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Pontine hypoplasia in children with periventricular leukomalacia.

BACKGROUND AND PURPOSE The brain stem in patients with periventricular leukomalacia (PVL) appears smaller than normal on MR imaging, but few reports have described this feature, and the number of patients has been relatively small. The present study was conducted to examine the hypothesis that the pons in patients with PVL is smaller than normal. MATERIALS AND METHODS Using MR imaging, we exa...

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ژورنال

عنوان ژورنال: Ultrasound in Obstetrics and Gynecology

سال: 2010

ISSN: 0960-7692

DOI: 10.1002/uog.8516